Gardening advice: The first week in March is the best time to prune roses. The Knockout variety and all other of the shrub-type roses can be pruned as far back as desired. Climbing roses don't usually need pruning, except to remove dead canes as needed. Once new growth begins fertilize with a half-cup of 10-10-10 fertilizer. Repeat the fertilizer every 4-6 weeks during the growing season and water as needed during drought. You'll be rewarded with bushes full of bloom.